Flash Purification Systems

ROUTINE FLASH PURIFICATION:

✓ Small but mighty
✓ Maximum flowrate of up to 300 ml/min @ max. 20 bar
✓ low rate accuracy +/- 2% over 20-250ml/min @ 5-16bar
✓ Quaternary gradient valve – step: +/- 0.1%
✓ Suitable for a comprehensive range of columns
✓ 4G to 800G Flash Columns for Routine Purification
✓ RFID: Universal: non-restrictive system
✓ load&Go technology: Automatic injection valve for Dryload with pack_ULTRA
✓ Flow rate accuracy collector: +/- 2%
✓ 15” touchscreen

ULTRA PERFORMANCE FLASH PURIFICATION:

✓ Maximum flow rate of up to 300ml/min @ max. 20bar
✓ Flow rate accuracy +/- 2% over 20-250mL/min @ 5-16bar
✓ Quaternary gradient valve – step: +/- 0.1%
✓ Easily use columns in formats F0004 to F0800 optimum flow rate             ✓ RFID Dry-Load & column Universal: non-restrictive system
✓ Load&Go technology: Automatic injection valve for DryLoad
✓ Flow rate accuracy collector: +/- 2%
✓ iELSD Detection
✓ Pump, fraction collector, integrated detectors, valves & columns leak detection
✓ Solvents and waste level monitoring
✓ 15” touchscreen

✓ Maximum flow rate of up to 250 ml/min @ max. 50 bar
✓ Flow rate accuracy +/- 2% over 20-200ml/min @ 5-40bar
✓ Quaternary gradient valve – step: +/- 0.1%
✓  RFID readers for flash and prep columns, loops and dryloads for each position
✓ iElSD Detection
✓ Pump, fraction collector, integrated detectors, valves & columns leak detection
✓ Solvents and waste level monitoring
✓ Upgradable with MS Upgradable with AS, 2nd fraction collector, injection pump
✓ 15” touchscreen

PROCESS FLASH PURIFICATION:

✓ Your ideal tool for high-throughput purification of raw product
✓ Big brother of the puriFlash XS 520 Plus
✓ Can purify a small to large amount of your product of interest with minimal runs
✓ Maximum flow rate of up to 400 ml/min @ max. 35 bar
✓ Quaternary gradient valve – step: +/- 0.1%
✓ RFID: Universal, non-restrictive system RFID Dry-Load & column w/ pack-Process
✓ Pump, fraction collector, integrated detectors, valves & columns leak detection
✓ 15” touchscreen

✓ Maximum flow rate of up to 825ml/min @ max. 15 bar
✓ Quaternary gradient valve – step: +/- 0.1%
✓ RFID: Universal. Non-restrictive system RFID Dry-Load & column w/ pack-Process
✓ Pump, fraction collector, integrated detectors, valves & columns leak detection
✓ Solvents and waste level monitoring
✓ Production continuity on the same device, regardless of the scale-up factor
✓ 15” touchscreen

Preparative Purification Systems

✓ For routine purification, complex mixtures, separation of impurities for later detection, trace enrichment, etc
✓ Maximum flow rate of up to 250ml/min @ max. 250 bar
✓ Small but Limitless
✓ 15” touchscreen

✓ Designed to excel in method development and purification of rare and high quality sample products
✓ Compatible with the use of sub-2 micron columns for maximum separating power
✓ Step into Ultra Purification
✓ Maximum flow rate of up to 125ml/min @ max. 400 bar
✓ 15” touchscreen

Peptides and Oligonucleotides

Purification Systems

✓ Designed for rigorous purification of peptides and oligonucleotides
✓ Compatible with the use of sub-2 micron columns for maximum separating power
✓ Combination of UV cell and optical path length reduces dead volume
✓ Maximum flow rate of up to 125ml/min @ max. 250 bar
✓ 15” touchscreen

Peripheral Detection Devices

DETECTORS:

✓ 200 – 400 nm (standard – except for the PF-020B intended for proteins)
✓ 200 – 800 nm (with UVextended pack for puriFlash® compatible with this option)
✓ Multi-wavelength and scan collection

✓ Compounds can be detected up to 100%
✓ Used very flexibly in the normal phase or in the reversed phase
✓ Used also in the methods of isocratic separation or multiple solvent gradients

MASS SPECTROMETERS:

✓ puriFlash MS/puriFlash MS-HMW/MS Splitter
✓ Detect and collect your compounds in accordance with their molecular weight, thanks to the single quadrupole mass spectrometer
✓ 3 available source types
            – ESI (Electrospray Ionization)
            – APCI (Atmospheric Pressure Chemical Ionization)
            – ASAP (Atmospheric Solid Analysis Probe)

DIFFERENTIAL REFRACTOMETERS:

✓ Non-destructive detector
✓ Products remain preserved whilst your purification output is optimized
✓ The refractive index detector is perfectly adapted to purification
✓ It’s high stability and sensitivity offers an excellent signal
✓ Detect and collect your compounds in accordance with molecular weight

The Intelligent Flash Family

Peripheral Production Devices

✓ The evaporator puriVap-6TM is the best solution for the evaporation of your samples with a volume from 2 ml to 60 ml 
✓ This compact system becomes indispensable because it enables up to 6 samples to be evaporated simultaneously, even if the dimensions differ

Sample Injection

SOLID INJECTION:

✓ Non-destructive detector
✓ Products remain preserved whilst your purification output is optimized
✓ The refractive index detector is perfectly adapted to purification
✓ It’s high stability and sensitivity offers an excellent signal
✓ Detect and collect your compounds in accordance with molecular weight

INJECTION LOOPS:

AUTOSAMPLER:

✓ With puriFlash®AS-1 it is possible to inject samples containing 500 μL to 50 mL with an automatic cleaning of the transfer tubes in-between injections

Rotary Evaporation

PURIFLASH R-VAP:

✓ Your laboratory Rotary Evaporator which is super intuitive, Ultra-efficient and simply indispensable.
✓ Gives you maximum flexibility by allowing you to evaporate your solvents in flasks up to 3L

✓ Proofs to be the instrument of choice for processing your fractions collected by the purification systems

Evaporative Performance:
Conditions: Solvent: ethyl acetate
Boiling point: 77.1°C
Volume: 100mL
Vacuum pressure: 150mbar
Heating temperature: 40°C
Cooling temperature: 5°C

Evaporation Time (Complete Drying): puriFlash® R-Vap =12.5 minutes

General Catalogue for AIS Consumables, Reagents & Instruments

https://www.interchim.com/pp.php?ref=3650