Advion Interchim Product

Over 50 years of experience in chromatography, Purification, Flash and Prep LC instrumentation and three decades of experience in design and development of novel mass spectrometry systems.

INDUCTIVELY COUPLED PLASMA-MASS SPECTROSCOPY (ICP-MS)

Solation ICP-MS is the ultimate instrument for multi-element analysis and provides high  sensitivity measurement of trace elements from a wide range of matrices including complex samples as urine, serum, plasma, whole blood and tissue, water, soil, food, beverage and agricultural samples.

COMPACT MASS SPECTROMETER (CMS)

  • Expression CMS with ESI, APCI or ASAP.
  • Atmospheric Solids Analysis Probe (ASAP/CMS).
  • Inert Atmospheric Solids Analysis Probe (iASAP/CMS).
  • Open Port Sampling Interface (OPSI).

THIN-LAYER CHROMATOGRAPHY-MASS SPECTROSCOPY INTERFACE

Plate Express – Automatically transfers the spot from the TLC Plate to the MS.

LC/MS

  • HPLC and (U)HPLC binary pumps 
  • Automated solvent selection of 4 solvents 
  • 6-way column switching.
  • Divert Valve
  • UV-Vis DAD
  • Column oven
  • Autosamplers with optional cooling
  • Modular and stackable design
  •  High-pressure mixing with optional degassing
  • Spectrometer (CMS) to provide seamlessly integrated LC/CMS.

AVANT (U)HPLC

Avant (U)HPLC is a high performance, liquid chromatography system that can be used as a standalone with UV and UV/Vis detector options or with expression compact Mass Spectrometer (CMS) to provide seamlessly integrated LC/CMS.

Flash Purification Systems

ROUTINE FLASH PURIFICATION

  • Small but mighty
  • Maximum flowrate of up to 300 ml/min @ max. 20 bar low rate accuracy +/- 2% over 20-250ml/min @ 5-16bar.
  • Quaternary gradient valve – step: +/- 0.1%.
  • Suitable for a comprehensive range of columns.
  • 4G to 800G Flash Columns for Routine Purification.
  • RFID: Universal: non-restrictive system.
  • load&Go technology.
  • Automatic injection valve for Dry-load with pack_ULTRA.
  • Flow rate accuracy collector: +/- 2%
  • 15” touchscreen

ULTRA PERFORMANCE FLASH PURIFICATION

  • Maximum flow rate of up to 300ml/min @ max. 20bar.
  • Flow rate accuracy +/- 2% over 20-250mL/min @ 5-16bar.
  • Quaternary gradient valve – step: +/- 0.1%.
  • Easily use columns in formats
  • F0004 to F0800 optimum flow rate.
  • RFID Dry-Load & column
  • Universal: non-restrictive system.
  • Load&Go technology
  • Automatic injection valve for Dry-Load.
  • Flow rate accuracy collector: +/- 2%.
  • iELSD Detection
  • Pump, fraction collector, integrated detectors, valves & columns leak detection.
  • Solvents and waste level monitoring.
  • 15” touchscreen

Ultra Performance Flash Purification

  • Maximum flow rate of up to 250ml/min @max 50 bar.
  • Flow rate accuracy +/- 2% over 20-200ml/min @ 5-40 bar.
  • Quaternary gradient valve – step: +/- 0.1%.
  • RFID readers for flash and prep columns, loops and dry-loads for each position.
  • iEISD Detection
  • Pump, fraction collector, integrated detectors, valves & columns leak detection.

PROCESS FLASH PURIFICATION

  • Your ideal tool for high-throughput purification of raw product.
  • Big brother of the puriFlash XS 520 Plus.
  • Can purify a small to large amount of your product of interest with minimal runs.
  • Maximum flow rate of up to 400 ml/min @ max. 35 bar.
  • Quaternary gradient valve – step: +/- 0.1%.
  • RFID: Universal, non-restrictive system RFID Dry-Load & column w/ pack-Process.
  • Pump, fraction collector, integrated detectors, valves & columns leak detection.
  • 15” touchscreen

PROCESS FLASH PURIFICATION

  • Maximum flow rate of up to 825ml/min @ max. 15 bar.
  • Quaternary gradient valve – step: +/- 0.1%.
  • RFID: Universal. Non-restrictive system RFID Dry-Load & column w/ pack-Process.
  • Pump, fraction collector, integrated detectors, valves & columns leak detection.
  • Solvents and waste level monitoring.
  • Production continuity on the same device, regardless of the scale-up factor.
  • 15” touchscreen

Preparative Purification Systems

  • For routine purification, complex mixtures, separation of impurities for later detection, trace enrichment, etc.
  • Maximum flow rate of up to 250ml/min @ max. 250 bar.
  • Small but Limitless
  • 15” touchscreen

Preparative Purification Systems

  • Designed to excel in method development and purification of rare and high quality sample products.
  • Compatible with the use of sub-2 micron columns for maximum separating power.
  • Step into Ultra Purification
  • Maximum flow rate of up to 125ml/min @ max. 400 bar.
  • 15” touchscreen

Peptides and Oligonucleotides Purification Systems

  • Designed for rigorous purification of peptides and oligonucleotides.
  • Compatible with the use of sub-2 micron columns for maximum separating power.
  • Combination of UV cell and optical path length reduces dead volume.
  • Maximum flow rate of up to 125ml/min @ max. 250 bar.
  • 15” touchscreen

MASS SPECTROMETERS

  • puriFlash MS/puriFlash MS-HMW/MS Splitter.
  • Detect and collect your compounds in accordance with their molecular weight, thanks to the single quadrupole mass spectrometer.
  • 3 available source types:

PURIFLASH XS-VAP

  • Your multifunction laboratory evaporator.
  • X-tra compact
  • X-tra intuitive
  • X-tra efficient
  • Heating system control
  • Two modes : Manual & Timer (setting evaporation time).
  • Light control inside the bath
  • Message-driven programming
  • Select gas rows and rack configuration.

Rotary Evaporation

Your laboratory Rotary Evaporator which is super intuitive, Ultra-efficient and simply indispensable. 
Gives you maximum flexibility by allowing you to evaporate your solvents in flasks up to 3L.
Proofs to be the instrument of choice for processing your fractions collected by the purification systems.

Evaporative Performance:

  • Conditions: Solvent: ethyl acetate.
  • Boiling point: 77.1°C
  • Volume: 100mL
  • Vacuum pressure: 150mbar
  • Heating temperature: 40°C
  • Cooling temperature: 5°C

Evaporation Time (Complete Drying): puriFlash® R-Vap =12.5 minutes.

SPE-LV6

The SPE-LV6 is a fully automated positive pressure workstation for sample preparation by SPE solid phase extraction.

Below are 9 Good Reasons to choose the SPE LV6:

    • Ensures Time Saving for Users during Sample Preparation.
    • Guarantees Repeatable Results with Positive Pressure Technology.
    • Creates your Purification Methods with Flexibility & Simplicity.
    • Improves your Sample Purification Step.
    • Automatic Rinsing Step avoids Cross Contaminations.
    • Innovative & Robust Technology.
    • Plug and Play in Few Minutes
    • Easy to Use without specific knowledge.
    • Cleaner & Safer Instrument with Solvent Waste Recoveries.

Peripheral Production Devices

Evaporator: PuriVap-6

  • The evaporator puriVap-6TM is the best solution for the evaporation of your samples with a volume from 2 ml to 60 ml.
  • This compact system becomes indispensable because it enables up to 6 samples to be evaporated simultaneously, even if the dimensions differ.

Peripheral Detection Devices

DETECTORS:

  • 200 – 400 nm (standard – except for the PF-020B intended for proteins).
  • 200 – 800 nm (with UVextended pack for puriFlash® compatible with this option).
  • Multi-wavelength and scan collection.
  • Compounds can be detected up to 100%.
  • Used very flexibly in the normal phase or in the reversed phase.
  • Used also in the methods of isocratic separation or multiple solvent gradients.

Peripheral Detection Devices

DIFFERENTIAL REFRACTOMETERS

  • Non-destructive detector
  • Products remain preserved whilst your purification output is optimized.
  • The refractive index detector is perfectly adapted to purification.
  • It’s high stability and sensitivity offers an excellent signal.
  • Detect and collect your compounds in accordance with molecular weight.

Sample Injection - AUTOSAMPLER

With puriFlash®AS-1 it is possible to inject samples containing 500 μL to 50 mL with an automatic cleaning of the transfer tubes in-between injections.

Triversa nanomate

  • The TriVersa NanoMate LESA® is the latest in chip-based electrospray ionization technology from Advion Interchim Scientific®.
  • It combines the benefits of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated ion source platform.
  • The TriVersa nanomate integrates with:

GENERAL CATALOGUE FOR AIS CONSUMABLES, REAGENTS & INSTRUMENTS

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